In the nightcap, Colorado scored five times in the eighth inning to break a tie, earn a 10-5 win and complete the doubleheader sweep. Michael Cuddyer hit a two-run double in the eighth to complete the seventh cycle in Rockies history.
The Reds looked to have the opener in control when they scored twice in the top of the ninth to open a 9-5 lead.
Cincinnati closer Aroldis Chapman entered in a non-save situation, and he walked all four batters he faced. Left fielder Charlie Culberson's free pass brought home a run and prompted Reds manager Bryan Price to replace Chapman with J.J. Hoover (1-9).
Pinch hitter Wilin Rosario hit a sacrifice fly, cutting the Rockies' deficit to 9-7. Right fielder Charlie Blackmon lined out to right for the second out before Stubbs hit Hoover's 1-0 pitch to left-center for a walk-off home run. It was Stubbs' 12th homer of the year.