Initial tests by doctors indicated that Indianapolis Colts wide receiver Reggie Wayne has a season-ending ACL injury from Sunday night's win over the Denver Broncos, according to ESPN.
Wayne was scheduled to have an MRI Monday.
One source told ESPN's Chris Mortensen that it "looks like he's out for the year" while another said the team is hoping the MRI "proves the doctors wrong on the ACL."
Wayne was injured when he tried to come back on an underthrown pass thrown by quarterback Andrew Luck midway through the fourth quarter of the game. He stayed down for several minutes before getting up and heading to the sideline with the crowd chanting "Reggie, Reggie, Reggie." He finished with five catches for 50 yards.
The 34-year-old has played in 189 straight games, the highest active streak in the NFL. The Colts have a bye this week. Their next game is Nov. 3 at the Houston Texans.