Virginia Attorney General Ken Cuccinelli: "This is a dark day for the American people, the Constitution, and the rule of law. This is a dark day for American liberty.

"This decision goes against the very principle that America has a federal government of limited powers; a principle that the Founding Fathers clearly wrote into the Constitution, the supreme law of the land. The Constitution was meant to restrict the power of government precisely for the purpose of protecting your liberty and mine from the overreaching hand of the federal government.

Club for Growth President Chris Chocola: "Today's Supreme Court decision is unfortunate. ObamaCare is a debacle and an unwarranted intrusion of the federal government into the marketplace. Republicans in Congress should continue to try to repeal ObamaCare in its entirety and replace it with market-based health care policies that will improve quality and bring down costs."

Senate Candidate George Allen of Virginia: "While disappointed in the Supreme Court's decision on President Obama's health care law, I believe it reinforces what is truly at stake during this pivotal election. This November the American people have an opportunity to choose new leadership in Washington who will listen to their voices and repeal this costly, harmful government health care law."

2008 GOP Vice Presidential Nominee Sarah Palin (via Twitter): "Obama lied to the American people. Again. He said it wasn't a tax. Obama lies; freedom dies."

U.S. Senate Candidate David Dewhurst of Texas: "Today's decision by the Supreme Court to uphold Obamacare as constitutional is reason number one why we need a Republican majority in the U.S. Senate to repeal this monstrous law. As I have said from the start of my campaign, my top priority on Day One in Washington will be to file legislation to repeal every word of Obamacare and throw the law in the trash can. Whether the individual mandate is characterized by the court as a mandate, or a tax, it is most certainly a disaster for America."

Virginia Gov. Bob McDonnell: "Today's Supreme Court ruling is extremely disappointing for Virginia and for America. The PPACA will create a costly and cumbersome system that will impair our country's ability to recover from these challenging economic times, infringes on our citizen's liberties, will harm small businesses, and will impose dramatic unfunded mandates on Virginia and all states. Simply put, this is a blow to freedom. America needs market-based solutions that give patients more choice, not less."

U.S. Sen. Rob Portman of Ohio: "While the Court has deemed the law constitutional as a tax on the American people, it is still flawed policy that is unaffordable for our families, our small businesses, and our government. The President's one-size-fits-all health care spending law is the centerpiece of a failed agenda that has increased economic uncertainty, stalled job creation, and deepened the spending hole that Washington."

New Jersey Gov. Chris Christie: "I've been clear from the very beginning that I do not believe a one-size-fits-all health care program works for the entire country and that each governor should have the ability to make decisions about what works best for their state. Today's Supreme Court decision is disappointing and I still believe this is the wrong approach for the people of New Jersey who should be able to make their own judgments about health care. Most importantly, the Supreme Court is confirming what we knew all along about this law -- it is a tax on middle class Americans."

Louisiana Gov: Bobby Jindal: "Ironically, the Supreme Court has decided to be far more honest about Obamacare than Obama was. They rightly have called it a tax. Today's decision is a blow to our freedoms. The Court should have protected our constitutional freedoms, but remember, it was the President that forced this law on us."

Former Republican presidential candidate Rick Santorum: "Today's outcome is the worst of all scenarios. Not only are our rights being taken away and Americans are being forced to do something we don't want to do, but now we are being burdened with the biggest permanent tax increase in our nation's history. This is a sad day."

Sen. Rand Paul of Kentucky: "Just because a couple people on the Supreme Court declare something to be 'constitutional' does not make it so. The whole thing remains unconstitutional. While the court may have erroneously come to the conclusion that the law is allowable, it certainly does nothing to make this mandate or government takeover of our health care right."

Sen. Roy Blunt of Missouri: "This decision does not change the fact that ObamaCare will lead to higher health care premiums, increased federal spending, and greater uncertainty for small business owners nationwide. That's why Congress must repeal this deeply flawed law in its entirety and replace it with thoughtful, common-sense reforms that put patients and doctors in control of health care -- not Washington bureaucrats."

Former presidential candidate Michele Bachmann: "This is a turning point in American history. We will never be the same again with this denial of liberty interests. But also it is a black cloud pragmatically speaking on economic recovery. There will be no hope of economic recovery between now and the election. We have exhausted now our legal solutions to be able to rid the nation of Obamacare. Now we have to look for a political solution."

Former presidential candidate and Texas Gov. Rick Perry: "This ruling will be a stomach punch to the American economy. It is a shocking disappointment to freedom-loving Americans desperate to get our country back on track. Obamacare is bad for the economy, bad for health care, bad for freedom. Americans have made clear their overwhelming opposition to its convoluted, burdensome and overreaching mandates.

Freedom was frontally attacked by passage of this monstrosity -- and the Court utterly failed in its duty to uphold the Constitutional limits placed on Washington. Now that the Supreme Court has abandoned us, we citizens must take action at every level of government and demand real reform, done with respect for our Constitution and our liberty."