(CNN) -

Sharifa lost her foot when the Syrian jets swooped down and fired missiles at the house.

Now the hijab-clad girl sits jaded in a dirty, hardscrabble displaced persons camp near Turkey, growing up fast, confused and far from home.

She needs crutches to move around and weeps for her lost limb.

"I can't get it back," she said.

But like many youth, Sharifa is resilient.

She teaches the younger kids at the camp mosque and, inshallah, wants to go back to her home village and do it there.

Her life has been hijacked. She's consumed by hope and grief, determination and despair.

"I just want to walk again," she says. "I just want to walk."

Sharifa is one of a lost generation uprooted by Syria's civil war.

She's one of the casualties of what the International Rescue Committee is calling a "regional humanitarian disaster," the widespread displacement caused by nearly two years of civil strife and war in Syria.

The IRC, one of the world's major refugee agencies, issued a chilling report Monday about the plight of refugees and internally displaced people.

More than 2.5 million Syrians have been uprooted, the IRC says.

Of those who have had to leave their homes, about 600,000 have fled, mostly to Jordan, Turkey, Lebanon and Iraq, which border Syria.

It's a replay of the population flight out of war-torn Iraq last decade. It conjures the wrenching flight in the 1940s during the birth of Israel, also next door to Syria.

"The Middle East is once again facing a human displacement tragedy," the IRC's commission on Syrian refugees said.

The IRC interviewed refugees in the border nations and got a grim view of life in the country.

Killings, attacks, arbitrary arrests, torture, abductions, rape, bombings and sexual violence. Loss of infrastructure and health care. Dwindling supplies of food, water and electricity. No school.

More than 60,000 people have died since the regime of Syrian leader Bashar al-Assad cracked down on peaceful protesters, a stance that set in motion what has become a nightmare, a civil war between the unyielding government and tenacious rebels.

The fighting has taken a sectarian overtone. The government is dominated by Alawites. The opposition, largely by Sunni Muslims.

People from other groups and religions in the diverse country have been caught in the crossfire. Some have joined the rebels. Others support the government.

Many sit tight and hope it ends. Others have fled to higher ground in Syria. Some to other countries.

People have embarked on treacherous journeys to safety outside Syria, scurrying from Homs and Hama to Lebanon, Daraa to Jordan, Aleppo and Idlib to Turkey, and Syrian Kurdish neighborhoods to Iraq.

Many live in camps, but most are "urban refugees," scattered through villages, towns and cities seeking shelter anywhere it is available.

Some live with host families but others are packed into small, dingy and poorly maintained apartments. Some are squatters, staying put in schools, public buildings and unused spaces.

"Every time it rains, we live in a pool of mud," said a 60-year-old woman from Daraa, interviewed by the IRC. She and seven others in Jordan share a room with a dirt floor and leaky roof.