The organization came to prominence during the Syrian uprising, and has claimed several high-profile strikes at the heart of the Syrian capital in the past several months.

The group explained that Tuesday's attack had three stages: first, a suicide car bomb carrying 9 tons of explosives detonated at the gates of the building; second, 25 minutes later, a suicide bomber drove an ambulance carrying 1 ton of explosives, detonating where air force troops were awaiting treatment; third, a mortar barrage aimed at the site of the blast.

Lesch pointed out that even if an entire building were decimated, many other parts of the intelligence apparatus remain in Syria. The al-Assad family established the complex web to ensure that no single group had power, and other groups could step in if one group was undermined.

The singular importance of the AFI goes back to Hafez Assad, Bashar's father, Lesch explained. Hafez Assad was a commander in the air force in the 1960s before a coup enabled him to take control of Syria in 1970.

"The air force intelligence has always been close to the Assad family," he said.

As the war has dragged on, Bashar al-Assad has repeatedly blamed "terrorists" for the violence in his country. Opposition fighters blame his regime for causing most of the bloodshed. Between these two versions stands what has become increasingly apparent -- there are likely jihadists and foreign fighters active in Syria. Some of these fighters are with groups linked to al Qaeda.

Their presence, many experts say, makes it far less likely that the West would involve itself in the Syrian conflict.

Last September, Alexia Jade said, a Syrian air force intelligence officer pointed his gun at her head. The air force was trying to break up an anti-al-Assad protest.

"There was one thing in his eyes," she said. "'Shoot the target.' It did not matter that I was a woman."

Some of the protestors created a diversion near the air force officer, shouting and yelling at him. He turned and they all scattered. Jade and her friends escaped, she said, but four people were killed in the protest that day.

Everyone fears the air force intelligence branch of the Syrian military, she said.

Susan Ahmad believes the regime has laid down increasing firepower to get back at those it perceives have attacked it. She also used an alias, fearing reprisals if she spoke to a reporter using her real name.

"They arrest more people, humiliate more people, harass more people," she said. "Maybe it's a way of boosting the soldiers' confidence. They let them do what they want and kill who they want."

On Tuesday morning, Ahmad still headed to her teaching job in central Damascus. She couldn't take public transportation. All roads leading to the capital were closed, and men at a checkpoint would not grant entry to most civilians, she said.

"The city is closed," Ahmad said. "All cars were forced to turn around, so the roads are empty."

Businesses are closed.

The blasts were among a barrage of explosions, gunfire and shelling reported from the Damascus area early Tuesday, suggesting the civil war may be zeroing in further on the Syrian capital.

"This is the largest blast I have ever felt since the uprising began," said Omar al-Khani, an opposition activist. "One of my windows is blown out, and neighbors' plates were knocked down from the table to the ground."

Less than half an hour later, al-Khani said, there was another explosion, followed by intermittent gunfire as a thick plume of smoke unfurled across the capital.

In the Damascas suburb of Harasta, violence continued in the form of shelling, opposition activists said. At least one person was killed and several homes destroyed "due to the heavy and indiscriminate shelling" of the suburb, the Local Coordination Committees of Syria said.

There were also reports of shelling in Aleppo and Idlib provinces.

Rebel forces took complete control of the town of Maaret al-Numan in Idlib province after 48 hours of clashes and shelling from regime forces. A highway connecting Damascus to Aleppo runs through the town.

Omar Abo alHoda, a citizen journalist in Idlib province, told CNN that over a year ago, Syrian troops set up eight military posts in the town, which has a population of about 140,000 people. The bases were to protect the highway from opposition attacks, with each post having between 70 and 100 Syrian troops, along with tanks, heavy and light weapons among other resources, he said.

Local residents claim troops used the posts as bases to launch attacks on civilian areas.

On Monday afternoon, thousands of rebel troops overran the military posts, using tanks, rocket fire, rocket-propelled grenades and gunfire, alHoda said. The regime responded with heavy firepower. Some troops were killed, the journalist said, and others were captured by the opposition.