Yothers has had only a handful of acting roles since "Family Ties" ended in 1989. She played the lead in "Lovelace The Musical," a 2004 stage show based on the life of former porn actress Linda Lovelace. She also appeared on VH1's "Celebrity Fit Club" and "Celebrity Fit Club: Boot Camp." In January 2012 she was featured on the ABC show "Celebrity Wife Swap," where she traded places with Niecy Nash of "Reno 911!" and "Clean House" fame. In February 2013, Yothers was also featured on an episode of the TLC series "What Not To Wear."