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TV's biggest casting changes

POSTED: 01:17 PM PDT Jun 09, 2011    UPDATED: 11:00 PM PDT Apr 15, 2014 

Take a look back at some of the more memorable casting changes in the history of television.

Cheers, Rebecca, Kirstie Alley
17 / 52
Charles/Burrows/Charles Productions

She was replaced with Kirstie Alley, who played businesswoman and on-again-off-again bar manager Rebecca Howe over the show's final six seasons.

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